If you have an important point to make, don't try to be subtle or clever. Use a pile driver. Hit the point once. Then come back and hit it again. Then hit it a third time -- a tremendous whack.

Set the time after which the current quote is refreshed. Use a tool like Plash (MacOS) to set this page to your desktop's background. Tap the image to toggle unnecessary interface elements.

To load the site with the interface not showing, and with a certain refresh rate, set querystring parameters like so: https://andiquote.org/?showInterface=0&refreshDuration=300.